Quantitative Whole Body Autoradiography (QWBA)

As part of its comprehensive preclinical ADME services, XBL provides Quantitative Whole Body Autoradiography (QWBA) study support. State-of-the-art instrumentation and facilities combined with industry expertise allow XBL to produce the highest quality autoradiography data. XBL incorporates Histological Verification of Site Specific Radioactivity (HVSSR) to provide the most accurate analysis of the distribution of derived radioactivity. XBL offers fully integrated services based on many years of experience to ensure a successful ADME program. Studies may be conducted as non-GLP or fully GLP compliant studies.

XBL's comprehensive QWBA services include:

Quantitative / Qualitative Whole Body Autoradiography

• Tissue Distribution
• Placental Transfer
• Melanin Binding
• Large Animal Organ or Tissue Autoradiography
• Microautoradiography
• whole blood calibration and QC standards

Histological Verification of Site Specific Radioactivity (HVSSR)

• Using Raytest AIDA Software

Turnkey Study Services

• Study Design
• Pharmacokinetics
• Dosimetry Calculations
• Presentation Grade Images
• Integration with Excretion Balance and Metabolite Profiling and ID

Supportive Data for Other Areas

• Oncology
• Pathology
• Toxicology
• Neuroscience
• Cardiovascular

New QWBA Laboratory Features

• Dedicated Darkroom
• HEPA Filtered Air Circulation
• Temperature and Humidity Control and Monitoring