In vivo - ADME PK/TK

XenoBiotic Laboratories (XBL) maintains AAALAC-accredited, USDA-registered animal facilities. We are equipped to conduct in-life studies in rat (intact or bile/jugular vein cannulated), mouse and dog. Study types include:

• Mass balance
• Tissue distribution
• Metabolite radioprofiling
• Metabolite identification
• Pharmacokinetics
• Toxicokinetics
• Cassette PK
• Drug-drug interaction
• Metabolism enzyme
mapping/induction/inhibition
• Bioavailability screening for various routes of administration