Major instrumentation and systems

• 19 LC-MS units with LC/MS/MS capability
  • - AB/Sciex API 5000 (4)
  • - AB/Sciex 4000 Q-Trap
  • - AB/Sciex 4000, Q-Star XL
  • - AB/Sciex API 4000 (7)
  • - PE-Sciex API-3000 (3)
  • - PE-Sciex API-365 (1)
  • - Thermo LTQ XL
  • - Thermo TSQ Quantum Ultra
  • - Thermo LTQ Orbitrap XL
• Tomtec Quadra 3 (2) and Quadra 96 (2) SPE liquid handling workstations
• PE Janus liquid handling workstation
• MultiPROBE® II automated liquid handling system (2)
• Picoview® Nanospray Sources PV150 & PV400
• 35 HPLC systems (Thermo, Shimadzu and Waters) including Thermo accela UPLC and 3 Shimadzu UFLC XR
• Radioactivity monitors (Raytest Ramona-Star, IN/US Systems ß-RAM Model 3, AIM Research Co. ARC™ Stop Flow and v. ARC™ Dynamic Flow (2), Packard Radiomatic™ Flow Scintillation Analyzer)
• PDA, UV, refractive index (RI) and fluorescence detectors
• Packard TopCount® NXT™ Microplate scintillation and luminescence counters (3)
• Bruker 500 MHz NMR with ¹H, ¹³C, ¹⁹F, ¹⁵N probes
• Waters Empower2 chromatography management system
• Gas Chromatographic system (Agilent Technologies) with a variety of detectors
• Watson LIMS™ Laboratory Information Management System
• Debra LIMS for ADME studies
• PE Tri-Carb 3100TR liquid scintillation counters (2)
• Beckman LS 6000 liquid scintillation counters (4)
• Harvey biological sample oxidizers (6)
• Rotary evaporators (3)
• High-speed centrifuges/ultracentrifuges
• Xenon Arc Lamp and Photoreaction chambers
• FTIR
• Dianorm GD-4 Equilibrium Dialysis unit
• Thermo Savant automated environmental SpeedVac® systems
• Fujifilm BAS 1800II & BAS 5000 Phosphor image analysis systems
• Cell culture laboratory complete with laminar flow hoods and incubators.
• BIO-TEK Synergy HT multi-detection microplate reader
• MSD Sector ECL Imager 6000
• Syngene G:Box Chemi Gel Imaging System
• Applied Biosystems 7500 Real Time PCR System
• Vibratome 9800 Cryomacrotome (2)
• AIDA Image Analysis Software
• -20 C Walk-in Freezers (7)
• -80 C Cryo-Freezers (10)