Sample analysis for PK and metabolism evaluation

One of XenoBiotic Laboratories' (XBL's) core capabilities is identifying and fully characterizing low level metabolites using state-of-the-art instrumentation and some of the most experienced staff in the industry.

XBL provides comprehensive sample analysis and metabolism study services

• Metabolite radioprofiling, characterization, and structure identification utilizing specially designed LC/MS/MS systems combined with tandem detectors such as PDA and RAM
• Radioprofiling with highly sensitive Topcount® and ARC™ Stop Flow radioactivity detectors
• Pharmacokinetic evaluation of active metabolites in all phases of clinical and pre-clinical development using multiple component (parent drug and key metabolites) assay methods
• High-capacity LC/MS/MS sample analysis
• Bulk metabolite isolation and purification with structural elucidation (1-D and 2-D 1H and 13C NMR)
• BA/BE sample analysis