XBL * A subsidiary of Lab Testing Division, WuXi AppTec Inc. WuXi AppTec XBL * A subsidiary of Lab Testing Division, WuXi AppTec Inc. WuXi AppTec
Thursday, October 30, 2014

Employment opportunities

Open Positions
Ongoing Positions

A note about ongoing positions:
These are positions for which XBL maintains an open enrollment policy. These are not currently open positions, however, XBL will contact candidates (whose information we have on file) that are a good match in the event that one of these positions opens up.

Open Positions

    Quality Assurance Auditor

Responsibilities:

Include but are not limited to: inspecting/auditing analytical/bioanalytical studies performed according to Good Laboratory Practices (FDA, EPA, and OECD); reviewing study data and reports; auditing software/system validation documents, summarizing findings and reporting to study directors/principal investigators and management; maintaining GLP-required documentation; keeping an accurate schedule of inspection activities; conducting facility, vendor and subcontractor audits.

Qualifications:

The successful candidate will have a BA/BS degree in a related scientific discipline and a minimum 2-yr QA experience working in a GLP-regulated environment; CRO experience is preferred. Candidate must be a fast learner who works well with numbers, is detail-oriented and highly organized, works well with people, and has excellent verbal and written communication skills.

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    Associate Scientist - Bioanalytical

Responsibilities:

Will under supervision, perform routine laboratory techniques, calcuations, tabulate and record results. Candidates must be able to prepare standard solutions used in laboratory, ability to calibrate and maintain equipment and assist senior staff with experiment set up and execution.

Qualifications:

The successful candidate must have a Bachelor's Degree in chemistry, biology, or a related discipline or any similar combination of education. Knowledge of bioanalytical assays is desirable. Experience working in a pharmaceutical R&D is also an asset.

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    Associate Scientist - In-Life/Laboratory Animal Science

Responsibilities:

Under supervision, participate in preclinical study related activities including animal care, dosing, sample collection, processing and analysis for rodent and non-rodent preclinical studies, perform data analysis, data checking and instrument/assay set up, operation and maintenance.

 

Qualifications:

The successful candidates must have an Associates or Bachelors degree in biology, animal science, or a related discipline to work on in-life phases of pre-clinical drug discovery and development areas. Experience working as a veterinarian technician with animal dosing technique is preferred. Must be willing to perform animal handling and caret/assay set up, operation and maintenance.

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    Quality Control Associate

Responsibilities:

Reviewing of bioanalytical notebooks to ensure adherence to protocols, reviewing raw data to ensure integrity, checking data summary to ensure accuracy preparing and reviewing bioanalytical reports.

 

Qualifications:

The successful candidate should have a BA/BS degree in science; must enjoy working with numbers; detail oriented and organized; experience in a GLP environment; skilled in written and verbal communication; excellent interpersonal skills; good math and computer skills (MS Word/Excel).

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    Technical Writer/Editor

Responsibilities:

Duties include editing and proofreading rough drafts received from R&D scientists for grammar, accuracy, clarity, consistency, style, organization, and conformance to corporate, government, and American Chemical Society style guide formats. Other duties inlcude assisting in preparing the following: study protocols and research reports for submission to government agencies and sponsors; in-house standard operating procedures; reports and abstracts for publication and/or presentation. Perform other duties as assigned.

 

Qualifications:

The successful candidate must possess a B.A. or B.S. degree with knowledge of biological and/or chemical sciences desired. 1-2 years of relevant industrial experience in technical publication/documentation is also preferred. Prior experience in a CRO is highly desirable. Candidates must also be detailed-oriented and proficient in a Microsoft Windows environment, with an emphasis on Microsoft Word, Excel, PowerPoint and Adobe Acrobat. Superior communications, interpersonal, presentation, and organizational skills are also essential. The successful candidate must be a self-starter, team player and have the dedication and driving energy to work in a fast-paced and challenging environment.

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    Study Director for Preclinical

Responsibilities:

Duties will include serving as a Study Director in the areas of ADME/PK studies. The successful individual selected for this position will supervise preclinical projects; provide leadership in the delivery of services to clients; review work produced by project teams; has strong problem solving ability; and ensure the staff fulfills their responsibilities in accordance with protocols, project contracts, and XBL policies, procedures, and SOPs. This individual will also represent company in client interaction, ensuring that projects are delivered on time, within budget, and according to client expectations.

 

Qualifications:

Successful candidates will demonstrate a thorough understanding of scientific principles and GLP regulations, successful candidates must have an Advanced degree or equivalent industrial experience. The individual must have deep knowledge and hands-on experience in dose preparation, animal dosing, sample collection, sample analysis, and sample processing techniques for mass balance PK and metabolite profiling/ID; knowledge in QWBA is helpful. Prior experience in DEBRA LIMS is highly desirable. Knowledge in laboratory animal care and facility management, as well as IACUC function, is a must. Candidate must be well versed in drug discovery and development, etc. as well as extensive protocol and report writing experience. The successful candidate must be hands-on, well organized, and a team player. Candidates must also be detailed-oriented, proficient in a Microsoft Windows environment; and possess superior interpersonal, presentation, and organizational skills.

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    Group Leader - Autoradioagraphy

Responsibilities:

Duties will include supervising preclinical projects; providing leadership in the delivery of services to clients; review work produced by project teams; candidate will have strong problem solving abilites; initiate, plan, and implement staff development programs related to Autoradiography and ADME; and ensure the staff fulfills their responsibilities in accordance with protocols, project contracts, and XBL policies, procedures, and SOPs. This individual will also represent company in client interaction, ensuring that projects are delivered on time, within budget, and according to client expectations.

 

Qualifications:

Successful candidates must possess an advanced degree (Ph.D. preferred) in Chemistry, Biology, or a related discipline along with a minimum of 5 years hands-on, Autoradiography or related industrial experience, and advanced knowledge of Autoradiography/ADME concepts (ie. study design, current methods and validations, data interpretation, etc.). Candidate must be well versed in drug discovery and development, etc. as well as extensive protocol and report writing experience. The successful candidate must be hands-on, with supervisory experience, a good trainer, well organized, and a team player. Candidates must also be detailed-oriented, proficient in a Microsoft Windows environment; and possess superior interpersonal, presentation, and organizational skills.

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    Senior Research Scientist - Bioanalytical

Responsibilities:

Ability to identify drug metabolites using liquid chromatography-tandem mass spectrometry, NMR, and other analytical methodologies. Elucidation of metabolic pathways involves the identification and quantification of metabolites in biological matrices (e.g., blood, plasma, excreta) using HPLC with radioactivity detection and/or LC-MS/MS. Implements new techniques and instrumentation to improve technical operations. Prepares scientific reports that document the analytical results and interpretation for the identification of drug metabolites.

 

Qualifications:

Will have a Ph.D. in Chemistry preferably natural product chemistry or related field equivalent combination of education and experience that provides the knowledge, skills, and abilities to perform the job. Experience in structural characterization and identification of drug metabolites using LC/MS/MS. Experience and knowledge of drug biotransformation and identification of drug metabolites. Experience in analytical method development using mass spectrometry and spectral data interpretation. Experience with radioisotope handling (e.g., 3H, 14C)biochemical techniques and in vivo and in vitro metabolism. Experience and knowledge of Good Laboratory Practices (GLP). Experience and knowledge in design of NMR experiments, operation, and data interpretation as applied to identification of unknowns is a plus. Highly skilled in conducting research, data interpretation and writing reports. Proven track record of analytical method development (HPLC, LC-MS, LC-MS/MS).

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Ongoing Positions

ASSISTANT/ASSOCIATE SCIENTIST
Preclinical Research

Responsibilities:

  • Under supervision of senior scientist, participate in preclinical study related activities including animal care, dosing, sample collection, processing and analysis for rodent and non-rodent preclinical studies
  • Perform data analysis, data checking, report preparation and instrument/assay set up, operation and maintenance

Qualifications:

  • A.S. or B.S. degree in biology, animal science, or related discipline
  • Experience or knowledge in animal handling or animal care is desirable but not necessary; training available
  • A certificate of LAT or above is a plus

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CHEMIST/ASSOCIATE SCIENTIST
Drug Metabolism/Environmental/Pharmaceutical Chemistry Areas

Responsibilities:

  • Preparation of biological samples
  • Performs routine analytical chemistry assays
  • Instrument set up, operation, and maintenance
  • Support senior staff with experiment set up and execution

Qualifications:

  • Experience in/knowledge of chromatography, sample preparation, wet chemistry, isolation/separation, and radiotracer techniques is desirable
  • Working in a regulated environment, following SOPs and adhering to pertinent regulations including Good Laboratory Practices (GLP)
  • BS or MS in science (chemistry, biochemistry, or related discipline)

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QA SPECIALIST (various levels)

Responsibilities:

  • Inspect/audit research studies to assure compliance with both government regulations and federal guidelines as well as with company policies
  • Audit/inspect laboratory studies, review data, write reports and summarize results from inspections/audits, and assist in overall functions of QA
  • Maintain written records of inspections/audits and do follow-up to verify that any corrective action required has been implemented
  • Assist in writing/updating standard operating procedures
  • Support scientific staff through participation in training and orientation presentations
  • Interact with Sponsors through site visits and requests for information

Qualifications:

  • BA/BS degree in related scientific discipline or equivalent experience
  • Experience working in a GLP/GMP or GCP regulated research environment
  • Knowledge of government regulations related to clinical/non-clinical research is helpful
  • Enjoy working with numbers, detail oriented and highly organized.
  • Skilled in written and verbal communication, excellent interpersonal skills
  • Prior laboratory and QA experience is highly desirable, but training will be provided
  • Good math and computer skills (MS Word/Excel)

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RESEARCH SCIENTIST PHARMACOKINETICS

Responsibilities:

  • Responsible for PK/TK analysis and report writing in support of client sponsored preclinical and clinical projects.
  • The successful candidate must have hands on experience with PK analysis software such as WinNonlin, and must be familiar with ADME studies in drug development.

Qualifications:

  • Requirements - Ph.D. in Pharmacokinetics or related field with 1-2 years industrial experience or MS with 7+ year's relevant industrial experience.
  • Strong written and verbal skills, highly organized, excellent computer skills, strong interpersonal and communication skills required.
  • Prior experience in CRO is highly desirable.

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RESEARCH SCIENTIST PRE-CLINCIAL GROUP

Responsibilities:

  • Serve as study director while working closely with in-life technical support staff and members of the metabolism group.
  • Design study protocols, participate in study initiation/dosing, supervise study conduct, and write study reports, as well as communicate with sponsors as primary contact person.

Qualifications:

  • Strong written and verbal skills, highly organized, excellent computer skills, strong interpersonal and communication skills.
  • The successful candidate must have superior multitasking skills, be able to manage multiple projects, and meet project timelines.
  • Must be familiar with ADME studies in drug development, current industry guidance's, and worldwide GLP regulations.
  • Requirements - Ph.D. in Pharmaceutical Science, Pharmacology, Biochemistry, Medicinal Chemistry, Toxicology or related field and 4+ years relevant hands-on industrial experience,
  • Prior experience in CRO is highly desirable.

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STAFF SCIENTIST/RESEARCH SCIENTIST
Mass Spectrometry Group

Responsibilities:

  • Utilize existing analytical methods in the LC/MS analysis of drug entities
  • Daily operation and instrument maintenance and troubleshooting
  • Develop and validate new and challenging analytical methods for new chemical entities
  • May serve as Study Directors/Principal Investigators
  • Data summary and report writing

Qualifications:

  • Experience in analytical method development/validation using mass spectrometry and spectral data interpretation
  • Experience in operating the modern quadrupole mass spectrometers, such as the Sciex API 4000 series, to analyze organic, organometallic and biological samples
  • Knowledge of all aspects of assay development including sample extraction and preparation, and chromatography
  • Working in a regulated environment, following SOPs and adhering to pertinent regulations including Good Laboratory Practices (GLP)
  • Excellent organizational and communication skills, work independently
  • PhD/MS in chemistry, mass spectrometry or related field and 1-4 years of experience preferred. Candidates with a B.S and 4-6 years of experience in assay method development and operation of LC/MS will also be considered

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